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> Cure for AIDS in sight?, the "Berlin Patient", stem cells, and coincidence
TreeFitty
post Dec 14 2010, 05:49 AM
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Here's something that should provide some interesting research in the months/years to follow:

QUOTE
Doctors who carried out a stem cell transplant on an HIV-infected man with leukaemia in 2007 say they now believe the man to have been cured of HIV infection as a result of the treatment, which introduced stem cells which happened to be resistant to HIV infection.

The man received bone marrow from a donor who had natural resistance to HIV infection; this was due to a genetic profile which led to the CCR5 co-receptor being absent from his cells. The most common variety of HIV uses CCR5 as its ‘docking station’, attaching to it in order to enter and infect CD4 cells, and people with this mutation are almost completely protected against infection.

The case was first reported at the 2008 Conference on Retroviruses and Opportunistic Infections in Boston, and Berlin doctors subsequently published a detailed case history in the New England Journal of Medicine in February 2009.

They have now published a follow-up report in the journal Blood, arguing that based on the results of extensive tests, “It is reasonable to conclude that cure of HIV infection has been achieved in this patient.”

main article and more detailed info


Basically, his immune system was emptied via chemotherapy. Then the donor HIV-resistant stem cells were put in, they filled up the immune system, and took over.

The process was long and grueling but he appears to no longer have HIV from various tests.


Thoughts? Obviously there is going to be a TON of research to follow with different people/conditions/etc.


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